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SINGLE - IC Antibodies / Non-EU
Monoclonal Mouse Anti-Human

IL-1

Clone: FIB3
Isotype: IgG1

Cat.No.
Format
Size
Datasheet
RUO
GM-4162
FITC
100 Tests

IL-1 is strongly expressed upon activation of monocytes and macrophages. IL-1 affects a wide range of cells and organs. Its spectrum of action is similar to that of TNF.

The FIB3 antibody permits the analysis of activated human monocytes, macrophages as well as myeloid dendritic cells using flow cytometry. To allow intracellular accumulation of IL-1 (prevent secretion), cells of interest can be pretreated with e.g. Brefeldin A (2 µg/ml) for 18 hours before analyses.