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SINGLE - SURFACE Antibodies / EU
Monoclonal Mouse Anti-Human
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CD14
Clone: MEM18
Isotype: IgG1
| Cat.No.
|
Format |
Size |
Datasheet |
| CE |
GM-4091 |
purified
|
0,2mg |
|
| CE |
GM-4092 |
FITC |
100
Tests |
|
| CE |
GM-4093 |
PE |
100
Tests |
|
CD14 is a GPI-anchored molecule expressed by virtually all human
monocytes and macrophages and – to a lesser degree - granulocytes.
CD14 together with Toll-like receptor 4 and MD-2 forms the LPS-receptor
complex that recognizes and signals the presence of LPS. While
CD14 has no signaling structure its main role seems to be the
binding of LPS.
The MEM18 antibody permits the identification and enumeration
of leukocytes using flow cytometry. MEM18 has been also used
for functional studies since this antibody blocks the interaction
of LPS with CD14 on monocytes.
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