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SINGLE - IC Antibodies / EU
Monoclonal Mouse Anti-Human
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IFN-
Clone: GZ4
Isotype: IgG1
| Cat.No.
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Format |
Size |
Datasheet |
| CE |
GM-4172 |
FITC |
100
Tests |
|
Interferon 
is a type-2 interferon that is produced mainly by T-cells and
NK-cell upon cellular activation. Human CD8 T-cells, isolated
from individuals after viral infection or vaccination, release
IFN-
upon exposure to the corresponding viral antigens in vitro.
The GZ4 antibody permits the analysis of activated human T-cells
and T-cell clones as well as NK cells using flow cytometry.
To allow intracellular accumulation of IFN-
(prevent secretion), cells of interest can be pretreated with
e.g. Brefeldin A (2 µg/ml) for 18 hours before analyses.
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